Can a drug that repairs DNA prevent noise-induced hearing loss?

by Daniel Fink, MD, Chair, The Quiet Coalition

This press release from Northern Arizona University discusses a professor’s research on a new drug to see if it can prevent noise-induced hearing loss. Noise causes the production of reactive oxygen species in the cochlea, damaging delicate hair cells. The new drug, derived from a plant found in the Amazon, helps repair DNA and that might help prevent noise-induced hearing loss.

I’m always puzzled, though, that in the U.S. we try to find “a pill for every ill,” rather than focusing on preventing disease.

People want a pill to help them lose weight, rather than eating right and exercising.

They want creams to reduce wrinkles and age spots, rather than avoiding the sun.

And they want a pill to prevent hearing loss.

The professor doing the research, O’neil Guthrie, states “[e]ven after more than 100 years of research on hearing loss, there is still no widely accepted biomedical treatment or prevention.” I would have to disagree with him. I’m not sure what he means by a “biomedical treatment or prevention,” but avoiding loud noise, or using hearing protection, certainly prevents noise-induced hearing loss. And that’s what I recommend.

Because if something sounds too loud, it IS too loud.

Dr. Daniel Fink is a leading noise activist based in the Los Angeles area. He is the founding chair of The Quiet Coalition, an organization of science, health, and legal professionals concerned about the impacts of noise on health, environment, learning, productivity, and quality of life in America. Dr Fink also is the interim chair of Quiet Communities’ Health Advisory Council, and he served on the board of the American Tinnitus Association from 2015-2018.

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